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What kind of
life will you live

when there is finally a cure?

Together, we can move ME/CFS & Long COVID research further, faster.

Complex diseases require collaboration

ME/CFS and Long COVID disrupt many body systems. Traditional research looks at one system at a time. That approach doesn’t work.

That’s where Open Medicine Foundation (OMF) comes in.  As a nonprofit, we’ve raised $45 million to fund multisystem collaborative research.  OMF brings world-renowned scientists together to study, diagnose, treat, and cure complex diseases.

It’s a bold dream.  It’s the path that will get you back to a fulfilling life.   

How do you get to an answer faster?


Once we understand how ME/CFS and Long COVID develop, researchers can pinpoint targets for intervention.


ME/CFS and Long COVID are difficult conditions to diagnose. We need specific biomarkers and definitive tests. 


Currently, there are very few treatments and they only target symptoms. OMF will launch treatment trials in 2023.

access to
quality care

OMF provides medical education to help healthcare providers understand the challenges of multisystem disease.

OMF Supported Collaborative Centers

CHU Sainte-Justine/Université de Montréal

ME/CFS Collaborative
Research Center

at the CHU Sainte-Justine
Université de Montréal

Alain Moreau, PhD

Clinical and scientific intervention studies
View the research
Melbourne, Australia

ME/CFS Collaboration

at Melbourne, Australia

Chris Armstrong, PhD

Precision research program
View the research
Medical professional pointing to the word Education

OMF Supported Medical Education Resource Center (MERC)

at Bateman Horne Center

Lucinda Bateman, MD
Medical Education Director

Medical Education Director
More about MERC

We take a multisystem approach

Human body

Neuroendocrine System: Dysfunctions in the hypothalamic-pituitary-adrenal (HPA) axis and hypothalamic-pituitary-gonadal (HPG) axis have been observed, leading to abnormalities in stress response, sex hormone levels, and autonomic nervous system regulation. 


Immune System: The immune system is composed of white blood cells, antibodies, and other components. It defends the body against infections and diseases, helping to maintain overall health


Cardiovascular System:  The cardiovascular system, comprising the heart, blood vessels, and blood, is responsible for transporting oxygen, nutrients, hormones, and waste products throughout the body. Its efficient functioning ensures the delivery of essential substances and the removal of waste products.


Metabolism:  Metabolism involves dysregulation in energy production, particularly in ATP synthesis and mitochondrial function. Abnormalities in carbohydrate, lipid, and amino acid metabolism have also been observed. Understanding these metabolic dysfunctions can lead to symptoms such as fatigue and muscle pain.


Genetics: Genetics may contribute to an individual's susceptibility to multisystem disease, including variations in immune system genes, genes involved in energy metabolism, and genes related to neurotransmitter function. 


Multiomics:  Multiomics combines various omics technologies such as genomics, transcriptomics, and proteomics. By analyzing multiple layers of biological data, multiomics provide a comprehensive understanding of the molecular mechanisms underlying multisystem diseases. 


Diagnostics:  Diagnostic studies help identify specific biomarkers, imaging techniques, and diagnostic criteria that aid in distinguishing different diseases within the multisystem spectrum. 


Treatments:  Treatment studies evaluate the efficacy and safety of potential interventions. By conducting rigorous clinical trials and treatment studies, researchers can refine existing therapies, develop new interventions, and provide evidence-based guidelines for healthcare providers. 


Systems Biology

Systems biology:  Systems biology is an interdisciplinary approach that combines biology, mathematics, and computational analysis. It helps identify key pathways, biomarkers, and potential therapeutic targets, leading to personalized and more effective treatments for multisystem disease patients.


Pathogens:  Infections can trigger or exacerbate symptoms, leading to increased fatigue, pain, and cognitive difficulties. Pathogens can also contribute to immune system dysregulation and inflammation. 


Studies funded by OMF

By funding studies that examine multiple systems, researchers can see how ME/CFS and Long COVID develop. This approach will lead to more effective treatments and improved quality of life.

Click on each system to read a description.

Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

What are the advantages of giving from your Donor Advised Fund (DAF)?

  • Your gifts to your donor advised fund entitle you to an immediate income tax deduction at the time of contribution.
  • You avoid capital gains tax on appreciated assets you place in your donor advised fund.
  • Your fund’s investment gains accumulate tax free.
  • Funds are distributed to Open Medicine Foundation in your name and immediately put to use to support our worldwide research efforts.

How do I make a donation through my DAF?

Just click on the DAF widget below. It is simple and convenient to find your fund among the over 900 funds in our system.

Still can’t find your fund? 

  • Request a grant distribution through your Donor Advised Fund sponsor
  • Be sure to use OMF’s EIN #26-4712664
  • You can also designate OMF as a beneficiary for your Donor Advised Fund
  • Questions? Give us a call at 650-242-8669